TBK1 antibody (AA 440-729)

Catalog No. ABIN3016268

The Rabbit Polyclonal anti-TBK1 antibody has been validated for WB and IHC. It is suitable to detect TBK1 in samples from Human.

Quick Overview for TBK1 antibody (AA 440-729) (ABIN3016268)

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TBK1 Antibody

Binding Specificity: AA 440-729

Sequence: RKGIRWLIEL IKDDYNETVH KKTEVVITLD FCIRNIEKTV KVYEKLMKIN LEAAELGEIS DIHTKLLRLS SSQGTIETSL QDIDSRLSPG GSLADAWAHQ EGTHPKDRNV EKLQVLLNCM TEIYYQFKKD KAERRLAYNE EQIHKFDKQK LYYHATKAMT HFTDECVKKY EAFLNKSEEW IRKMLHLRKQ LLSLTNQCFD IEEEVSKYQE YTNELQETLP QKMFTASSGI KHTMTPIYPS SNTLVEMTLG MKKLKEEMEG VVKELAENNH ILERFGSLTM DGGLRNVDCL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 440-729 of human TBK1/NAK (NP_037386.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Alternative Name: TBK1

Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.,TBK1,FTDALS4,NAK,T2K,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Kinase of Akt,TBK1

Molecular Weight: 83 kDa

Gene ID: 29110

UniProt: Q9UHD2

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome