FES antibody (AA 120-420)

Catalog No. ABIN3016277

This Rabbit Polyclonal antibody specifically detects FES in WB. It exhibits reactivity toward Human.

Quick Overview for FES antibody (AA 120-420) (ABIN3016277)

Target: FES (Feline Sarcoma Oncogene (FES))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FES antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FES Antibody

Binding Specificity: AA 120-420

Sequence: WQQLQQELTK THSQDIEKLK SQYRALARDS AQAKRKYQEA SKDKDRDKAK DKYVRSLWKL FAHHNRYVLG VRAAQLHHQH HHQLLLPGLL RSLQDLHEEM ACILKEILQE YLEISSLVQD EVVAIHREMA AAAARIQPEA EYQGFLRQYG SAPDVPPCVT FDESLLEEGE PLEPGELQLN ELTVESVQHT LTSVTDELAV ATEMVFRRQE MVTQLQQELR NEEENTHPRE RVQLLGKRQV LQEALQGLQV ALCSQAKLQA QQELLQTKLE HLGPGEPPPV LLLQDDRHST SSSEQEREGG R

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-420 of human FES (NP_001137256.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FES

Target: FES (Feline Sarcoma Oncogene (FES))

Alternative Name: FES

Background: This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.,FES,FPS,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,FES

Molecular Weight: 78 kDa/85 kDa/86 kDa/93 kDa

Gene ID: 2242

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2