HNF1B antibody (AA 100-200)

Catalog No. ABIN3017359

This anti-HNF1B antibody is a Rabbit Polyclonal antibody detecting HNF1B in WB. Suitable for Human.

Quick Overview for HNF1B antibody (AA 100-200) (ABIN3017359)

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNF1B Antibody

Binding Specificity: AA 100-200

Sequence: TEEAAEQRAE VDRMLSEDPW RAAKMIKGYM QQHNIPQREV VDVTGLNQSH LSQHLNKGTP MKTQKRAALY TWYVRKQREI LRQFNQTVQS SGNMTDKSSQ D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HNF1B (NP_000449.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Alternative Name: HNF1B

Background: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.,HNF1B,FJHN,HNF-1-beta,HNF-1B,HNF1beta,HNF2,HPC11,LF-B3,LFB3,MODY5,TCF-2,TCF2,VHNF1,Epigenetics & Nuclear Signaling,Transcription Factors,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,HNF1B

Molecular Weight: 44 kDa/46 kDa/58 kDa/61 kDa

Gene ID: 6928

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation