SIRT2 antibody (AA 288-389)

Catalog No. ABIN3020852

This Rabbit Polyclonal antibody specifically detects SIRT2 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for SIRT2 antibody (AA 288-389) (ABIN3020852)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SIRT2 Antibody

Binding Specificity: AA 288-389

Sequence: EKAGQSDPFL GMIMGLGGGM DFDSKKAYRD VAWLGECDQG CLALAELLGW KKELEDLVRR EHASIDAQSG AGVPNPSTSA SPKKSPPPAK DEARTTEREK PQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 288-389 of human SIRT2 (NP_036369.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:10 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Alternative Name: SIRT2

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.,SIRT2,SIR2,SIR2L,SIR2L2,sirtuin 2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,SIRT2

Molecular Weight: 30 kDa/35 kDa/39 kDa/41 kDa/43 kDa

Gene ID: 22933

UniProt: Q8IXJ6