CRP antibody

Catalog No. ABIN302086

This Mouse Monoclonal antibody specifically detects CRP in ELISA and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for CRP antibody (ABIN302086)

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: C2

Product Details anti-CRP Antibody

Purpose: Anti-CRP Purified

Specificity: The mouse monoclonal antibody C2 recognizes human CRP, an 117 kDa plasma acute phase protein, it recognizes the antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.

Cross-Reactivity (Details): Human

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Purified human CRP

Isotype: IgG1

Application Details

Application Notes: ELISA: The antibody C2 has been tested as the capture antibody in a sandwich ELISA for analysis of human CRP.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

References for anti-CRP antibody (ABIN302086)

Meyer, Hartmann, Krause, Blankenstein, Mueller-Chorus, Oster, Miethe, Keusgen: "CRP determination based on a novel magnetic biosensor." in: Biosensors & bioelectronics, Vol. 22, Issue 6, pp. 973-9, (2007) (PubMed).

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: CRP

Background: C-reactive protein,The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein composed of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa, physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.

Gene ID: 1401

UniProt: P02741

Pathways: Carbohydrate Homeostasis