Desmin antibody (AA 121-470)
Quick Overview for Desmin antibody (AA 121-470) (ABIN3021115)
Target
See all Desmin (DES) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 121-470
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Sequence
- NYIEKVRFLE QQNAALAAEV NRLKGREPTR VAELYEEELR ELRRQVEVLT NQRARVDVER DNLLDDLQRL KAKLQEEIQL KEEAENNLAA FRADVDAATL ARIDLERRIE SLNEEIAFLK KVHEEEIREL QAQLQEQQVQ VEMDMSKPDL TAALRDIRAQ YETIAAKNIS EAEEWYKSKV SDLTQAANKN NDALRQAKQE MMEYRHQIQS YTCEIDALKG TNDSLMRQMR ELEDRFASEA SGYQDNIARL EEEIRHLKDE MARHLREYQD LLNVKMALDV EIATYRKLLE GEESRINLPI QTYSALNFRE TSPEQRGSEV HTKKTVMIKT IETRDGEVVS EATQQQHEVL
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 121-470 of human Desminmin (NP_001918.3).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid freeze / thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Desmin (DES)
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Alternative Name
- DES
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Background
- This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.,DES,CSM1,CSM2,LGMD2R,desmin,Desmin,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Heart,Cardiac arrhythmias,DES
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Molecular Weight
- 53 kDa
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Gene ID
- 1674
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UniProt
- P17661
Target
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