TLR7 antibody (AA 30-230)

Catalog No. ABIN3021247

This Rabbit Polyclonal antibody specifically detects TLR7 in WB and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for TLR7 antibody (AA 30-230) (ABIN3021247)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TLR7 Antibody

Binding Specificity: AA 30-230

Sequence: FPKTLPCDVT LDVPKNHVIV DCTDKHLTEI PGGIPTNTTN LTLTINHIPD ISPASFHRLD HLVEIDFRCN CVPIPLGSKN NMCIKRLQIK PRSFSGLTYL KSLYLDGNQL LEIPQGLPPS LQLLSLEANN IFSIRKENLT ELANIEILYL GQNCYYRNPC YVSYSIEKDA FLNLTKLKVL SLKDNNVTAV PTVLPSTLTE L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human TLR7 (NP_057646.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TLR7 antibody (ABIN3021247)

Rezagholizadeh, Datta, Hasler, Nguon, Smokey, Chen: "TLR7 Mediates HIV-1 Tat-Induced Cellular Senescence in Human Astrocytes." in: Aging cell, Vol. 24, Issue 7, pp. e70086, (2025) (PubMed).

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.,TLR7,TLR7-like,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TLR7

Molecular Weight: 120 kDa

Gene ID: 51284

UniProt: Q9NYK1

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades