RHOC antibody (AA 1-193)
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- Target See all RHOC Antibodies
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
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Binding Specificity
- AA 1-193
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RHOC antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYIADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRQDEHTRRE LAKMKQEPVR SEEGRDMANR ISAFGYLECS AKTKEGVREV FEMATRAGLQ VRKNKRRRGC PIL
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RhoC (NP_001036144.1).
- Isotype
- IgG
- Top Product
- Discover our top product RHOC Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Alternative Name
- RHOC (RHOC Products)
- Background
- This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.,RHOC,ARH9,ARHC,H9,RHOH9,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Microtubules,RHOC
- Molecular Weight
- 22 kDa
- Gene ID
- 389
- UniProt
- P08134
- Pathways
- WNT Signaling, Cell-Cell Junction Organization
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