Syndecan 1 antibody (AA 25-240)

Catalog No. ABIN3021805

This Rabbit Polyclonal antibody specifically detects Syndecan 1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Syndecan 1 antibody (AA 25-240) (ABIN3021805)

Target: Syndecan 1 (SDC1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syndecan 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Syndecan 1 Antibody

Binding Specificity: AA 25-240

Sequence: VATNLPPEDQ DGSGDDSDNF SGSGAGALQD ITLSQQTPST WKDTQLLTAI PTSPEPTGLE ATAASTSTLP AGEGPKEGEA VVLPEVEPGL TAREQEATPR PRETTQLPTT HQASTTTATT AQEPATSHPH RDMQPGHHET STPAGPSQAD LHTPHTEDGG PSATERAAED GASSQLPAAE GSGEQDFTFE TSGENTAVVA VEPDRRNQSP VDQGAT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CD138/Syndecan-1 (NP_002988.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Syndecan 1

Target: Syndecan 1 (SDC1)

Alternative Name: SDC1

Background: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.,SDC1,CD138,SDC,SYND1,syndecan,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Hematopoietic Progenitors,Neuron marker,Synapse marker,SDC1

Molecular Weight: 32 kDa

Gene ID: 6382

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism