TYR antibody (AA 20-340)

Catalog No. ABIN3021852

This anti-TYR antibody is a Rabbit Polyclonal antibody detecting TYR in WB and IHC. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for TYR antibody (AA 20-340) (ABIN3021852)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TYR Antibody

Binding Specificity: AA 20-340

Sequence: FPRACVSSKN LMEKECCPPW SGDRSPCGQL SGRGSCQNIL LSNAPLGPQF PFTGVDDRES WPSVFYNRTC QCSGNFMGFN CGNCKFGFWG PNCTERRLLV RRNIFDLSAP EKDKFFAYLT LAKHTISSDY VIPIGTYGQM KNGSTPMFND INIYDLFVWM HYYVSMDALL GGSEIWRDID FAHEAPAFLP WHRLFLLRWE QEIQKLTGDE NFTIPYWDWR DAEKCDICTD EYMGGQHPTN PNLLSPASFF SSWQIVCSRL EEYNSHQSLC NGTPEGPLRR NPGNHDKSRT PRLPSSADVE FCLSLTQYES GSMDKAANFS F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-340 of human TYR (NP_000363.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TYR antibody (ABIN3021852)

Zhang, Wang, Yu, Jiang, Yue, Liu: "Identification of a gene encoding microphthalmia-associated transcription factor and its association with shell color in the clam Meretrix petechialis." in: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, Vol. 225, pp. 75-83, (2018) (PubMed).

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: TYR

Background: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.,TYR,ATN,CMM8,OCA1,OCA1A,OCAIA,SHEP3,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,TYR

Molecular Weight: 42 kDa/60 kDa

Gene ID: 7299

UniProt: P14679