MITF antibody (AA 1-280)

Catalog No. ABIN3021855

This anti-MITF antibody is a Rabbit Polyclonal antibody detecting MITF in WB. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for MITF antibody (AA 1-280) (ABIN3021855)

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MITF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MITF Antibody

Binding Specificity: AA 1-280

Sequence: MLEMLEYNHY QVQTHLENPT KYHIQQAQRQ QVKQYLSTTL ANKHANQVLS LPCPNQPGDH VMPPVPGSSA PNSPMAMLTL NSNCEKEGFY KFEEQNRAES ECPGMNTHSR ASCMQMDDVI DDIISLESSY NEEILGLMDP ALQMANTLPV SGNLIDLYGN QGLPPPGLTI SNSCPANLPN IKRELTESEA RALAKERQKK DNHNLIERRR RFNINDRIKE LGTLIPKSND PDMRWNKGTI LKASVDYIRK LQREQQRAKE LENRQKKLEH ANRHLLLRIQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MITF (NP_937801.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MITF antibody (ABIN3021855)

Zhang, Yue, Jiang, Wang, Liu: "Identification of an MITF gene and its polymorphisms associated with the Vibrio resistance trait in the clam Meretrix petechialis." in: Fish & shellfish immunology, Vol. 68, pp. 466-473, (2018) (PubMed).

Zhang, Wang, Yu, Jiang, Yue, Liu: "Identification of a gene encoding microphthalmia-associated transcription factor and its association with shell color in the clam Meretrix petechialis." in: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, Vol. 225, pp. 75-83, (2018) (PubMed).

Target Details for MITF

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Alternative Name: MITF

Background: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.,MITF,CMM8,COMMAD,MI,WS2,WS2A,bHLHe32,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,MITF

Molecular Weight: 40 kDa/46 kDa/52 kDa/55 kDa/56 kDa/57 kDa/58 kDa

Gene ID: 4286

UniProt: O75030

Pathways: Chromatin Binding