Coagulation Factor IX antibody (AA 29-192)

Catalog No. ABIN3022174

This Rabbit Polyclonal antibody specifically detects Coagulation Factor IX in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Coagulation Factor IX antibody (AA 29-192) (ABIN3022174)

Target: Coagulation Factor IX (F9)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coagulation Factor IX antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Coagulation Factor IX Antibody

Binding Specificity: AA 29-192

Sequence: TVFLDHENAN KILNRPKRYN SGKLEEFVQG NLERECMEEK CSFEEAREVF ENTERTTEFW KQYVDGDQCE SNPCLNGGSC KDDINSYECW CPFGFEGKNC ELDVTCNIKN GRCEQFCKNS ADNKVVCSCT EGYRLAENQK SCEPAVPFPC GRVSVSQTSK LTRA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-192 of human Factor IX / F9 (NP_000124.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Coagulation Factor IX

Target: Coagulation Factor IX (F9)

Alternative Name: F9

Background: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.,F9,F9 p22,FIX,HEMB,P19,PTC,THPH8,F9p22,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,Coagulation,F9

Molecular Weight: 47 kDa/51 kDa

Gene ID: 2158

UniProt: P00740