Apolipoprotein C-II antibody (AA 1-101)

Catalog No. ABIN3022521

The Rabbit Polyclonal anti-Apolipoprotein C-II antibody (ABIN3022521) specifically detects Apolipoprotein C-II in WB. The antibody is reactive with Human samples.

Quick Overview for Apolipoprotein C-II antibody (AA 1-101) (ABIN3022521)

Target: Apolipoprotein C-II (APOC2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apolipoprotein C-II antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Apolipoprotein C-II Antibody

Binding Specificity: AA 1-101

Sequence: MGTRLLPALF LVLLVLGFEV QGTQQPQQDE MPSPTFLTQV KESLSSYWES AKTAAQNLYE KTYLPAVDEK LRDLYSKSTA AMSTYTGIFT DQVLSVLKGE E

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human APOC2 (NP_000474.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Apolipoprotein C-II

Target: Apolipoprotein C-II (APOC2)

Alternative Name: APOC2

Background: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.,APOC2,APO-CII,APOC-II,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Heart,Lipids,Lipoproteins/Apolipoproteins,Cardiovascular diseases,Heart disease,APOC2

Molecular Weight: 11 kDa

Gene ID: 344

UniProt: P02655

Pathways: Lipid Metabolism