Caspase 6 antibody (AA 24-293)

Catalog No. ABIN3022545

The Rabbit Polyclonal anti-Caspase 6 antibody is suitable to detect Caspase 6 in samples from Human. It has been validated for WB and IF.

Quick Overview for Caspase 6 antibody (AA 24-293) (ABIN3022545)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Caspase 6 Antibody

Binding Specificity: AA 24-293

Sequence: AFYKREMFDP AEKYKMDHRR RGIALIFNHE RFFWHLTLPE RRGTCADRDN LTRRFSDLGF EVKCFNDLKA EELLLKIHEV STVSHADADC FVCVFLSHGE GNHIYAYDAK IEIQTLTGLF KGDKCHSLVG KPKIFIIQAC RGNQHDVPVI PLDVVDNQTE KLDTNITEVD AASVYTLPAG ADFLMCYSVA EGYYSHRETV NGSWYIQDLC EMLGKYGSSL EFTELLTLVN RKVSQRRVDF CKDPSAIGKK QVPCFASMLT KKLHFFPKSN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-293 of human Caspase-6 (NP_001217.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: CASP6

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.,CASP6,MCH2,caspase-6,Caspase-6 p18,Caspase-6,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CASP6

Molecular Weight: 22 kDa/33 kDa

Gene ID: 839

UniProt: P55212

Pathways: Apoptosis, Caspase Cascade in Apoptosis