POLR2C antibody (AA 1-275)

Catalog No. ABIN3022547

Product Details anti-POLR2C Antibody

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Binding Specificity: AA 1-275

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2C antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Sequence: MPYANQPTVR ITELTDENVK FIIENTDLAV ANSIRRVFIA EVPIIAIDWV QIDANSSVLH DEFIAHRLGL IPLISDDIVD KLQYSRDCTC EEFCPECSVE FTLDVRCNED QTRHVTSRDL ISNSPRVIPV TSRNRDNDPN DYVEQDDILI VKLRKGQELR LRAYAKKGFG KEHAKWNPTA GVAFEYDPDN ALRHTVYPKP EEWPKSEYSE LDEDESQAPY DPNGKPERFY YNVESCGSLR PETIVLSALS GLKKKLSDLQ TQLSHEIQSD VLTIN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human RPB3/POLR2C (NP_116558.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:20 - 1:50

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POLR2C

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Alternative Name: POLR2C (POLR2C Products)

Background: This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.,POLR2C,RPB3,RPB31,hRPB33,hsRPB3,Epigenetics & Nuclear Signaling,Neuroscience,Neurodegenerative Diseases,POLR2C

Molecular Weight: 31 kDa

Gene ID: 5432

UniProt: P19387

Pathways: Regulatory RNA Pathways