Syndecan 2 antibody (AA 19-144)

Catalog No. ABIN3022588

The Rabbit Polyclonal anti-Syndecan 2 antibody has been validated for WB and IHC. It is suitable to detect Syndecan 2 in samples from Human. There is 1 publication available.

Quick Overview for Syndecan 2 antibody (AA 19-144) (ABIN3022588)

Target: Syndecan 2 (SDC2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syndecan 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Syndecan 2 Antibody

Binding Specificity: AA 19-144

Sequence: ESRAELTSDK DMYLDNSSIE EASGVYPIDD DDYASASGSG ADEDVESPEL TTSRPLPKIL LTSAAPKVET TTLNIQNKIP AQTKSPEETD KEKVHLSDSE RKMDPAEEDT NVYTEKHSDS LFKRTE

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human SDC2 (NP_002989.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Syndecan 2 antibody (ABIN3022588)

Rickelt, Hynes: "Antibodies and methods for immunohistochemistry of extracellular matrix proteins." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 71-72, pp. 10-27, (2018) (PubMed).

Target Details for Syndecan 2

Target: Syndecan 2 (SDC2)

Alternative Name: SDC2

Background: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.,SDC2,CD362,HSPG,HSPG1,SYND2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Growth factor,VEGF,Immunology & Inflammation,CD markers,Neuroscience,Cardiovascular,Angiogenesis,SDC2

Molecular Weight: 22 kDa

Gene ID: 6383

UniProt: P34741

Pathways: Glycosaminoglycan Metabolic Process