Syndecan 2 antibody (AA 50-130)

Catalog No. ABIN7224190

The Rabbit Polyclonal anti-Syndecan 2 antibody is suitable to detect Syndecan 2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Syndecan 2 antibody (AA 50-130) (ABIN7224190)

Target: Syndecan 2 (SDC2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syndecan 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Syndecan 2 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-Syndecan-2 Polyclonal Antibody

Specificity: Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Syndecan-2 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Syndecan 2

Target: Syndecan 2 (SDC2)

Alternative Name: Syndecan-2

Background: SDC2, HSPG1, Syndecan-2, SYND2, Fibroglycan, Heparan sulfate proteoglycan core protein, HSPG, CD antigen CD362The protein encoded by SDC2 (syndecan 2) is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

Molecular Weight: 22kD

Gene ID: 6383

UniProt: P34741

Pathways: Glycosaminoglycan Metabolic Process