ICOS antibody (AA 21-140)
Quick Overview for ICOS antibody (AA 21-140) (ABIN1513055)
Target
See all ICOS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 21-140
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Sequence
- EINGSANYEM FIFHNGGVQI LCKYPDIVQQ FKMQLLKGGQ ILCDLTKTKG SGNTVSIKSL KFCHSQLSNN SVSFFLYNLD HSHANYYFCN LSIFDPPPFK VTLTGGYLHI YESQLCCQLK
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-140 of human ICOS/CD278 (NP_036224.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid freeze / thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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Alternative Name
- ICOS
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Background
- The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.,ICOS,AILIM,CD278,CVID1,Immunology & Inflammation,CD markers,ICOS
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Molecular Weight
- 19 kDa/22 kDa
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Gene ID
- 29851
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UniProt
- Q9Y6W8
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Pathways
- Cancer Immune Checkpoints
Target
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