RUNX1 antibody (AA 150-250)

Catalog No. ABIN3022804

This Rabbit Polyclonal antibody specifically detects RUNX1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for RUNX1 antibody (AA 150-250) (ABIN3022804)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUNX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RUNX1 Antibody

Binding Specificity: AA 150-250

Sequence: AMKNQVARFN DLRFVGRSGR GKSFTLTITV FTNPPQVATY HRAIKITVDG PREPRRHRQK LDDQTKPGSL SFSERLSELE QLRRTAMRVS PHHPAPTPNP R

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human RUNX1 (NP_001745.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Alternative Name: RUNX1

Background: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.,RUNX1,AML1,AML1-EVI-1,AMLCR1,CBF2alpha,CBFA2,EVI-1,PEBP2aB,PEBP2alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Neuroscience,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,RUNX1

Molecular Weight: 20-28 kDa/37 kDa/48-51 kDa

Gene ID: 861

UniProt: Q01196