PMS1 antibody (AA 405-619)

Catalog No. ABIN3023148

This anti-PMS1 antibody is a Rabbit Polyclonal antibody detecting PMS1 in WB. Suitable for Human.

Quick Overview for PMS1 antibody (AA 405-619) (ABIN3023148)

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PMS1 Antibody

Binding Specificity: AA 405-619

Sequence: DCLNHQISIG DFGYGHCSSE ISNIDKNTKN AFQDISMSNV SWENSQTEYS KTCFISSVKH TQSENGNKDH IDESGENEEE AGLENSSEIS ADEWSRGNIL KNSVGENIEP VKILVPEKSL PCKVSNNNYP IPEQMNLNED SCNKKSNVID NKSGKVTAYD LLSNRVIKKP MSASALFVQD HRPQFLIENP KTSLEDATLQ IEELWKTLSE EEKLK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 405-619 of human PMS1 (NP_000525.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Alternative Name: PMS1

Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.,PMS1,HNPCC3,MLH2,PMSL1,hPMS1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,PMS1

Molecular Weight: 62 kDa/86 kDa/101 kDa/105 kDa

Gene ID: 5378

UniProt: P54277