ENPP2 antibody (AA 564-863)
Quick Overview for ENPP2 antibody (AA 564-863) (ABIN3023334)
Target
See all ENPP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 564-863
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Sequence
- DLGCTCDDKV EPKNKLDELN KRLHTKGSTE ERHLLYGRPA VLYRTRYDIL YHTDFESGYS EIFLMPLWTS YTVSKQAEVS SVPDHLTSCV RPDVRVSPSF SQNCLAYKND KQMSYGFLFP PYLSSSPEAK YDAFLVTNMV PMYPAFKRVW NYFQRVLVKK YASERNGVNV ISGPIFDYDY DGLHDTEDKI KQYVEGSSIP VPTHYYSIIT SCLDFTQPAD KCDGPLSVSS FILPHRPDNE ESCNSSEDES KWVEELMKMH TARVRDIEHL TSLDFFRKTS RSYPEILTLK TYLHTYESEI
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 564-863 of human ENPP2 (NP_001035181.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
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Alternative Name
- ENPP2
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Background
- The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.,ENPP2,ATX,ATX-X,AUTOTAXIN,LysoPLD,NPP2,PD-IALPHA,PDNP2,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Lipases,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,Heart,Lipids,Cardiovascular diseases,Heart disease,ENPP2
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Molecular Weight
- 98 kDa/101 kDa/105 kDa
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Gene ID
- 5168
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UniProt
- Q13822
Target
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