MMP11 antibody

Catalog No. ABIN3023460

Product Details anti-MMP11 Antibody

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP11 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide of human MMP11

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MMP11 antibody (ABIN3023460)

Zhou, Zhu, Luo, Gao, Dai, Li, Zuo: "MicroRNA-202-3p regulates scleroderma fibrosis by targeting matrix metalloproteinase 1." in: Biomedicine & pharmacotherapy, Vol. 87, pp. 412-418, (2017) (PubMed).

Target Details for MMP11

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Alternative Name: MMP11 (MMP11 Products)

Synonyms: SL-3 antibody, ST3 antibody, STMY3 antibody, Stmy3 antibody, MMP-11 antibody, matrix metallopeptidase 11 antibody, matrix metallopeptidase 11 L homeolog antibody, stromelysin-3 antibody, MMP11 antibody, Mmp11 antibody, mmp11.L antibody, LOC103694874 antibody

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.,MMP11,SL-3,ST3,STMY3,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP11

Molecular Weight: 54 kDa

Gene ID: 4320

UniProt: P24347