HLA-ABC antibody
Quick Overview for HLA-ABC antibody (ABIN3023755)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
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Purification
- Protein G affinity chromatography
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Immunogen
- Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.
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Isotype
- IgG2a kappa
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anti-HLA-ABC (HLA-ABC) antibody
HLA-ABC Reactivity: Human, Cow, Baboon, Cat, Monkey FACS, IP, IHC (fro), WB, IHC Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew, Chimpanzee, Gorilla FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Cat, Monkey, Primate FACS, IP, IHC (fro), IF, EIA Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Baboon, Macaque, Cat, Monkey, Primate, Chimpanzee FACS, IP, IHC (fro), IF, Func, EIA, DNA Mic Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyGMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (FITC)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 FITC
anti-HLA-ABC (HLA-ABC) antibody (PE)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibody (APC)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 APC
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Application Notes
- Optimal dilution of the HLA-ABC antibody should be determined by the researcher.\. Western blot: 1-2 μg/mL, Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the HLA-ABC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- HLA-ABC
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Alternative Name
- HLA-ABC (MHC I)
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Background
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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