TRIL antibody (C-Term)
Quick Overview for TRIL antibody (C-Term) (ABIN3023981)
Target
See all TRIL AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- TRIL Antibody / KIAA0644
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Purification
- Protein A affinity chromatography
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Immunogen
- A recombinant protein fragment from the C-terminal region of human TRIL was used as the immunogen for this antibody.
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Isotype
- IgG
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Application Notes
- Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TRIL (TLR4 Interactor with Leucine-Rich Repeats (TRIL))
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Alternative Name
- TRIL
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Background
- TRIL or TLR4 interactor with leucine rich repeats, is a protein encoded by the human KIAA0644 gene. TRIL protein sequence is highly conserved across species. It is expressed in a number of tissues with highest expression in brain, ovary, small intestine and spleen. TRIL is an accessory molecule that interacts with TLR3 and endosomal TLR4, enhancing their interaction with their ligands, poly(I:C) and LPS, and increasing the production of type I interferons in the innate immune response.
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Pathways
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response
Target
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