VLDLR antibody (C-Term)
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- Target See all VLDLR Antibodies
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This VLDLR antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G affinity chromatography
- Immunogen
- A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.
- Clone
- VLPR-1
- Isotype
- IgG1
- Top Product
- Discover our top product VLDLR Primary Antibody
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- Application Notes
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDLR antibody to be titered up or down for optimal performance.
1. Staining of FFPE tissue is enhanced by boiling sections in 10 mM Tris with 1 mM EDTA, pH 9 for 10-20 min followed by cooling at RT for 20 min.\. FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL (1)
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store the VLDLR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Target
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- Alternative Name
- VLDLR (VLDLR Products)
- Synonyms
- CARMQ1 antibody, CHRMQ1 antibody, VLDLRCH antibody, AA408956 antibody, AI451093 antibody, AW047288 antibody, vldlr antibody, very low density lipoprotein receptor antibody, very low density lipoprotein receptor S homeolog antibody, VLDLR antibody, Vldlr antibody, vldlr.S antibody
- Background
- Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
- Gene ID
- 7436
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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