ALDH1A1 antibody (AA 315-434)

Catalog No. ABIN3024144

The Mouse Monoclonal anti-ALDH1A1 antibody is suitable to detect ALDH1A1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for ALDH1A1 antibody (AA 315-434) (ABIN3024144)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALDH1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: AHDH1-1

Product Details anti-ALDH1A1 Antibody

Binding Specificity: AA 315-434

Purpose: ALDH1 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A human recombinant partial ALDH1A1 protein (AA 315-434) was used as the immunogen for this ALDH1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Titering of the ALDH1 antibody may be required for optimal performance.

1. FFPE testing requires sections to be boiled in pH 9 10 mM Tris with 1 mM EDTA for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: The ALDH1 antibody (with azide) can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: ALDH1

Background: ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

UniProt: P00352

Pathways: Dopaminergic Neurogenesis