CD147 antibody

Catalog No. ABIN3024283

The Mouse Monoclonal anti-CD147 antibody (Clone CB43) (ABIN3024283) specifically detects CD147 in FACS and IF. The antibody is reactive with Human samples.

Quick Overview for CD147 antibody (ABIN3024283)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD147 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Grade: Carrier-free

Clone: CB43

Product Details anti-CD147 Antibody

Purpose: Emmprin Antibody (azide and preservative free)

Purification: PEG precipitation

Immunogen: Native human leukocytes were used as the immunogen for the Emmprin antibody.

Isotype: IgM, kappa

Application Details

Application Notes: Optimal dilution of the Emmprin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Emmprin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: Emmprin

Background: CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

UniProt: P35613

Pathways: S100 Proteins