FZD9 antibody (Extracellular Domain, N-Term)

Catalog No. ABIN302482

This Rabbit Polyclonal antibody specifically detects FZD9 in IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FZD9 antibody (Extracellular Domain, N-Term) (ABIN302482)

Target: FZD9 (Frizzled Family Receptor 9 (FZD9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD9 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FZD9 Antibody

Binding Specificity: Extracellular Domain, N-Term

Specificity: This antibody detects Frizzled-9 (FZD9) at N-terminal extracellular domain.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: FZD9 antibody was raised against synthetic peptide from N-terminal extracellular domain of human FZD9 / Frizzled 9.

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for FZD9

Target: FZD9 (Frizzled Family Receptor 9 (FZD9))

Alternative Name: CD349 / FZD9 / Frizzled-9

Background: FZD9, previously named frizzled-3, is a Frizzled Receptor that mediates Wnt signaling. It may contribute to the Williams-Beuren syndrome described as supravalvular and aortic stenosis, and to infantile hypercalcemia.Synonyms: Fz-9, hFz9

Gene ID: 8326

NCBI Accession: NP_003499

UniProt: O00144

Pathways: WNT Signaling