POMC antibody (N-Term)

Catalog No. ABIN3025418

This Mouse Monoclonal antibody specifically detects POMC in ELISA, FACS, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for POMC antibody (N-Term) (ABIN3025418)

Target: POMC (Proopiomelanocortin (POMC))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This POMC antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: 57

Product Details anti-POMC Antibody

Binding Specificity: AA 1-24, N-Term

Purpose: POMC Antibody / ACTH / Synacthen / N-Terminal (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: An N-terminal peptide (within AA 1-24) from the Synacthen/ACTH region of human POMC was used as the immunogen for this POMC antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The optimal dilution of the ACTH / POMC antibody for each application should be determined by the researcher.

1. View the recombinant version of this < a href=../tds/recombinant-acth-antibody-mouse-monoclonal-r57-v3466>ACTH antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the POMC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for POMC

Target: POMC (Proopiomelanocortin (POMC))

Alternative Name: POMC

Background: POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour