Rabies Virus antibody

Catalog No. ABIN3025497

The Mouse Monoclonal anti-Rabies Virus antibody is suitable to detect Rabies Virus in samples from Lyssavirus rabies (RABV). It has been validated for ELISA and IF.

Quick Overview for Rabies Virus antibody (ABIN3025497)

Target: Rabies Virus (RABV)

Reactivity: Lyssavirus rabies (RABV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This Rabies Virus antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Clone: Rab-50

Product Details anti-Rabies Virus Antibody

Purpose: Rabies Virus Antibody

Purification: Protein G affinity chromatography

Immunogen: Purified virions of SAD-Vnukovo strain followed by Pitman-Moore strain was used as the immunogen for the Rabies Virus antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Rabies Virus antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Rabies Virus antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Rabies Virus

Target: Rabies Virus (RABV)

Alternative Name: Rabies Virus

Target Type: Virus

Background: Reacts with viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore. This mAb is useful in detecting rabies virus by ELISA and Western. It is capable of neutralizing rabies virus. Rabies virus (Neurotropic virus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumb like glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Lipid solvents destroy virus infectivity. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.