IFNA2 antibody

Catalog No. ABIN3025780

This anti-IFNA2 antibody is a Mouse Monoclonal antibody detecting IFNA2 in ELISA. Suitable for Human.

Quick Overview for IFNA2 antibody (ABIN3025780)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA2 antibody is un-conjugated

Application: ELISA

Clone: N39

Product Details anti-IFNA2 Antibody

Purification: Protein G affinity chromatography

Immunogen: Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.

Isotype: IgG kappa

Application Details

Application Notes: Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.\. ELISA: order BSA/azide-free format for coating

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Interferon alpha 2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for IFNA2

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Alternative Name: Interferon alpha 2

Background: Recognizes a protein of 16-27  kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This mAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C