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IL-24 antibody (AA 100-150)

IL24 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN302672
  • Target See all IL-24 (IL24) Antibodies
    IL-24 (IL24) (Interleukin 24 (IL24))
    Binding Specificity
    • 15
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-150
    Reactivity
    • 67
    • 10
    • 7
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 9
    Rabbit
    Clonality
    • 64
    • 8
    Polyclonal
    Conjugate
    • 32
    • 10
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-24 antibody is un-conjugated
    Application
    • 55
    • 28
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Specificity
    This antibody recognizes Interleukin 24 (IL24/Mda-7).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Protein G Chromatography
    Immunogen
    A portion of amino acids 100-150 of human IL-24 was used as the immunogen.
    Isotype
    IgG
    Top Product
    Discover our top product IL24 Primary Antibody
  • Application Notes
    Flow Cytometry. Western Blot: 0.5-3 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS, 0.05 % Sodium Azide, 0.2 % Gelatin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.
  • Target
    IL-24 (IL24) (Interleukin 24 (IL24))
    Alternative Name
    Interleukin-24 / IL24 (IL24 Products)
    Synonyms
    C49A antibody, FISP antibody, IL10B antibody, MDA7 antibody, MOB5 antibody, ST16 antibody, Mda7 antibody, St16 antibody, Mda-7 antibody, IL24 antibody, interleukin 24 antibody, IL24 antibody, Il24 antibody
    Background
    Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein
    Gene ID
    11009
    NCBI Accession
    NP_001172085
    UniProt
    Q13007
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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