Angiostatin antibody (AA 103-352)

Catalog No. ABIN3028464

The Rabbit Polyclonal anti-Angiostatin antibody (ABIN3028464) specifically detects Angiostatin in WB, ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Angiostatin antibody (AA 103-352) (ABIN3028464)

Target: Angiostatin (ANG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiostatin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Angiostatin Antibody

Binding Specificity: AA 103-352

Purpose: Angiostatin K1-3 Antibody

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 103-352) was used as the immunogen for this Angiostatin K1-3 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Angiostatin K1-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Angiostatin K1-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Angiostatin

Target: Angiostatin (ANG)

Alternative Name: Angiostatin K1-3

Background: Ang K1-3 is a proteolytic fragment of Plasminogen. It is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50 = 135nM).

UniProt: P00747

Pathways: Lipid Metabolism