RIPK2 antibody

Catalog No. ABIN302855

The Rabbit Polyclonal anti-RIPK2 antibody is suitable to detect RIPK2 in samples from Human. It has been validated for WB, IF and IHC (p).

Quick Overview for RIPK2 antibody (ABIN302855)

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RIPK2 Antibody

Specificity: This antibody reacts to a peptide corresponding to amino acids 508 to 522 of human origin.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide

Application Details

Application Notes: Immunocytochemistry. Immunohistochemistry on paraffin sections: 5 μg/mL. Western Blot: 1: 500 & 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline, containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.

Target Details for RIPK2

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Alternative Name: RIPK2

Background: RIPK2 belongs to the RIP subfamily of kinases. RIPK2 has an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and recruitment domain (CARD). RIPK2 interacts with CD40 or the tumor necrosis factor receptor.Synonyms: CARD-containing IL-1 beta ICE-kinase, CARDIAK, RICK, RIP-2, RIP-like-interacting CLARP kinase, RIP2, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2

Gene ID: 8767

NCBI Accession: NP_003812

UniProt: O43353

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades