CD86 antibody (AA 24-329)

Catalog No. ABIN3028554

The Rabbit Polyclonal anti-CD86 antibody (ABIN3028554) specifically detects CD86 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for CD86 antibody (AA 24-329) (ABIN3028554)

Target: CD86

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD86 Antibody

Binding Specificity: AA 24-329

Purpose: CD86 Antibody

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 24-329) was used as the immunogen for this CD86 antibody.

Isotype: IgG

Application Details

Application Notes: Titration of the CD86 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: The lyophilized CD86 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freeze/thaws.

Target Details for CD86

Target: CD86

Alternative Name: CD86

Background: Cluster of Differentiation 86 (also known as B7-2) is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. The antigen presentation coactivators B7-1 and B7-2/CD86, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation