Prothrombin antibody (AA 600-612)

Catalog No. ABIN3028573

This Rabbit Polyclonal antibody specifically detects Prothrombin in WB. It exhibits reactivity toward Rat.

Quick Overview for Prothrombin antibody (AA 600-612) (ABIN3028573)

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prothrombin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Prothrombin Antibody

Binding Specificity: AA 600-612

Purification: Antigen affinity

Immunogen: Amino acids 600-612 (THVFRLKRWMQKV-rat) were used as the immunogen for this Prothrombin antibody.

Isotype: IgG

Application Details

Application Notes: Titration of the Prothrombin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Prothrombin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Prothrombin

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Alternative Name: Prothrombin (Thrombin)

Background: F2 (Coagulation Factor II), also known as prothrombin and thrombin, is a serine protease that in humans is encoded by the F2 gene. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII(F8), and XIII(F13A1). Thrombin also inhibits coagulation by Activating protein C.

UniProt: P18292

Pathways: Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling