GR (AA 20-199) antibody

Catalog No. ABIN3028684

This Rabbit Polyclonal antibody specifically detects GR in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GR (AA 20-199) antibody (ABIN3028684)

Target: GR

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 20-199

Purpose: GR Antibody / Glucocorticoid receptor / NR3C1

Purification: Antigen affinity

Immunogen: Human recombinant NR3C1 protein (AA 20-199) was used as the immunogen for this GR antibody.

Isotype: IgG

Application Details

Application Notes: Titration of the GR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details

Target: GR

Background: The glucocorticoid receptor (GR, or GCR), also known as NR3C1, is the receptor to which cortisol and other glucocorticoids bind. GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response. The activated GR complex up-regulates the expression of anti-inflammatory proteins in the nucleus or represses the expression of pro-inflammatory proteins in the cytosol.