PIK3R1 antibody (AA 65-80)

Catalog No. ABIN3028926

This anti-PIK3R1 antibody is a Rabbit Polyclonal antibody detecting PIK3R1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for PIK3R1 antibody (AA 65-80) (ABIN3028926)

Target: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3R1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIK3R1 Antibody

Binding Specificity: AA 65-80

Purification: Antigen affinity

Immunogen: Amino acids 65-80 (ERGDFPGTYVEYIGRK-alpha subunit specific) was used as the immunogen for this PI3K antibody (100% human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: Titration of the PI3K antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Store the lyophilized PI3K antibody at 4°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PIK3R1

Target: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Alternative Name: PI3K

Background: Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. The PI3K p85 subunit family has two closely related members, alpha and beta. Both cDNAs encode p85 subunits, each of which is a 724-amino acid polypeptide. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.

UniProt: P27986

Pathways: TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect