TIMP4 antibody (AA 208-224)

Catalog No. ABIN3029140

Product Details anti-TIMP4 Antibody

Target: TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))

Binding Specificity: AA 208-224

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Amino acids 208-224 (YRGHLPLRKEFVDIVQP-human) were used as the immunogen for this TIMP4 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the TIMP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.2 mg/mL in 1X PBS with 50 % glycerol and 0.025 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the TIMP4 antibody at -20°C.

Target Details for TIMP4

Target: TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))

Alternative Name: TIMP4 (TIMP4 Products)

Synonyms: TIMP4 antibody, TIMP-4 antibody, timp4 antibody, TIMP metallopeptidase inhibitor 4 antibody, TIMP metallopeptidase inhibitor 4, tandem duplicate 3 antibody, tissue inhibitor of metalloproteinase 4 antibody, TIMP4 antibody, timp4.3 antibody, Timp4 antibody

Background: The tissue inhibitors of metalloproteinases(TIMPs) inhibit matrix metalloproteinases(MMPs), a group of peptidases involved in degradation of the extracellular matrix. The TIMP4 gene contains 5 exons that span 6 kb of genomic DNA. The gene is expressed as a 1.4-kb transcript abundant in heart and present at low levels in several other tissues. expressed TIMP4 inhibits MMPs in vitro. TIMP4 binds both progelatinase A and the C domain in a similar manner to that of TIMP-2.

UniProt: Q99727