MAPK6 antibody (pSer189)

Catalog No. ABIN3029714

The Rabbit Polyclonal anti-MAPK6 antibody has been validated for ELISA and IHC. It is suitable to detect MAPK6 in samples from Human.

Quick Overview for MAPK6 antibody (pSer189) (ABIN3029714)

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-MAPK6 Antibody

Binding Specificity: pSer189

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Chicken

Purification: Antigen affinity

Immunogen: This phospho-ERK3 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS189 of human ERK3.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-ERK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-ERK3 antibody (phospho-S189 and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MAPK6

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Alternative Name: ERK3

Background: ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

UniProt: Q16659

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C