Laminin antibody (AA 152-170)

Catalog No. ABIN3029737

This Rabbit Polyclonal antibody specifically detects Laminin in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Laminin antibody (AA 152-170) (ABIN3029737)

Target: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Laminin Antibody

Binding Specificity: AA 152-170

Purification: Antigen affinity

Immunogen: Amino acids 152-170 (WILERSLDDVEYKPWQYHA-human) were used as the immunogen for this LAMA2 antibody (100% mouse homology).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the LAMA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the LAMA2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Laminin

Target: Laminin (LAMA2) (Laminin, alpha 2 (LAMA2))

Alternative Name: LAMA2 Laminin 2 alpha

Background: Laminin 2 alpha is a protein that in humans is encoded by the LAMA2 gene. This gene is mapped to 6q22.33. Laminin, an extracellular protein, is a major component of the basement membrane. It is though to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

UniProt: P24043