Pkc beta 1 antibody (AA 542-671)

Catalog No. ABIN3029750

The Rabbit Polyclonal anti-Pkc beta 1 antibody is suitable to detect Pkc beta 1 in samples from Rat, Human and Mouse. It has been validated for WB.

Quick Overview for Pkc beta 1 antibody (AA 542-671) (ABIN3029750)

Target: Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pkc beta 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Pkc beta 1 Antibody

Binding Specificity: AA 542-671

Purpose: PKC beta Antibody / PRKCB

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 542-671) was used as the immunogen for this PKC beta antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the PKC beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PKC beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Pkc beta 1

Target: Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))

Alternative Name: PKC beta 1

Background: Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. Family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Family members also serve as major receptors for phorbol esters, a class of tumor promoters. PKC beta has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that it is activated by oxidative conditions in the cell, induces phosphorylation of < a href=../search_result.php?search_txt=shc>p66 (SHC) and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase < a href=../search_result.php?search_txt=pin1>PIN1.