APLP2 antibody (C-Term)

Catalog No. ABIN3029933

The Rabbit Polyclonal anti-APLP2 antibody is suitable to detect APLP2 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for APLP2 antibody (C-Term) (ABIN3029933)

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APLP2 Antibody

Binding Specificity: C-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human APLP2(EEKVINSKNKVDENMVID) was used as the immunogen for this APLP2 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the APLP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the APLP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Alternative Name: APLP2

Background: Amyloid beta(A4) precursor-like protein 2, also known as CDEBP, is a protein that in humans is encoded by the APLP2 gene. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. Along with APLP1, it is an important modulator of glucose and insulin homeostasis. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface expression by enhancing endocytosis.

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour