The Rabbit Polyclonal anti-PMP70 antibody is suitable to detect PMP70 in samples from Human, Mouse and Rat. It has been validated for WB, IF and IHC (p).
ABCD3
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 350
Application Notes
The stated application concentrations are suggested starting amounts. Titration of the PMP70 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the PMP70 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
PMP70 (ABCD3)
(ATP-Binding Cassette, Sub-Family D (Ald), Member 3 (ABCD3))
Alternative Name
PMP70
Background
70 kDa peroxisomal membrane protein (PMP70), also called ATP-binding cassette sub-family D member 3, is a protein that in humans is encoded by the ABCD3 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The gene was assigned to human chromosome 1p21-p22 by in situ hybridization. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders.