CEBPB antibody (AA 1-200)

Catalog No. ABIN3030344

Product Details anti-CEBPB Antibody

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Binding Specificity: AA 1-200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-200) was used as the immunogen for this C/EBP beta antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the C/EBP beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the C/EBP beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Alternative Name: C/EBP beta (CEBPB Products)

Synonyms: C/EBPbeta antibody, c/ebp-beta antibody, crp2 antibody, il6dbp antibody, lap antibody, nf-il6 antibody, tcf5 antibody, xC/EBPbeta antibody, cebpbb antibody, cb380 antibody, c/ebpb antibody, fe11e05 antibody, wu:fe11e05 antibody, CEBPB antibody, LOC100136165 antibody, C/EBP-beta antibody, CRP2 antibody, IL6DBP antibody, LAP antibody, NF-IL6 antibody, TCF5 antibody, IL-6DBP antibody, LIP antibody, NF-M antibody, Nfil6 antibody, Il6dbp antibody, CCAAT/enhancer binding protein beta antibody, CCAAT/enhancer binding protein beta L homeolog antibody, CCAAT/enhancer binding protein (C/EBP), beta antibody, CCAAT/enhancer-binding protein beta antibody, cebpb antibody, cebpb.L antibody, CEBPB antibody, LOC100136165 antibody, Cebpb antibody

Background: CCAAT/enhancer-binding protein beta, also known as is C/EBP beta, is a protein that in humans is encoded by the CEBPB gene. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the< a href=../search_result.php?search_txt=il-6>IL-6gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. C/EBP beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of C/EBP beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.

Gene ID: 1051

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation