Decorin antibody (AA 6-19)
Quick Overview for Decorin antibody (AA 6-19) (ABIN303057)
Target
See all Decorin (DCN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 6-19
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Specificity
- This antibody reacts to Decorin.
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Purification
- Protein G column
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Immunogen
- DCN antibody was raised against synthetic peptide corresponding to the amino acids 6 - 19 of human decorin conjugated to Keyhole Limpet Haemocyanin.
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Application Notes
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Immunohistochemistry on paraffin sections. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- PBS ( pH 7.2) containing 0.09 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Decorin (DCN)
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Alternative Name
- Decorin
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Background
- Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes.Synonyms: Bone proteoglycan II, DCN, PG-S2, PG40, SLRR1B
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Gene ID
- 1634
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NCBI Accession
- NP_001911
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UniProt
- P07585
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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