FGF1 antibody (AA 16-155)

Catalog No. ABIN3030929

The Rabbit Polyclonal anti-FGF1 antibody is suitable to detect FGF1 in samples from Human. It has been validated for WB, IHC (p) and ELISA (Standard).

Quick Overview for FGF1 antibody (AA 16-155) (ABIN3030929)

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Standard)

Product Details anti-FGF1 Antibody

Binding Specificity: AA 16-155

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 16-155) was used as the immunogen for this FGF1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the FGF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot (recombinant protein): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FGF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FGF1

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Alternative Name: FGF1

Background: Fibroblast growth factor 1 (acidic), also known as< a href=../search_result.php?search_txt=fgf1>FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. Human FGF1 shares 96 % amino acid sequence homology with both rat and mouse. The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is though to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.

UniProt: P05230

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway