KIN antibody (N-Term)
Quick Overview for KIN antibody (N-Term) (ABIN3031547)
Target
See all KIN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purification
- Antigen affinity
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Immunogen
- An amino acid sequence from the N-terminus of human KIN (ESHQRQLLLASENPQQF) was used as the immunogen for this KIN17 antibody (100% homologous in human, mouse and rat).
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Isotype
- IgG
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Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the KIN17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- -20 °C
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Storage Comment
- After reconstitution, the KIN17 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))
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Alternative Name
- KIN17
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Background
- DNA/RNA-binding protein KIN17, also known as BTCD, is a protein that in humans is encoded by the KIN gene. This gene is mapped to 10p14. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.
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UniProt
- O60870
Target
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