Leupaxin antibody (N-Term)

Catalog No. ABIN3031617

Product Details anti-Leupaxin Antibody

Target: Leupaxin (LPXN)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leupaxin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human Leupaxin (KKHLPDKQDHKASLD) was used as the immunogen for this Leupaxin antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Leupaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Leupaxin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Leupaxin

Target: Leupaxin (LPXN)

Alternative Name: Leupaxin (LPXN Products)

Synonyms: LDPL antibody, 4933402K05Rik antibody, A530083L21Rik antibody, AV278559 antibody, MGC140379 antibody, leupaxin antibody, hypothetical protein antibody, Leupaxin antibody, LPXN antibody, Lpxn antibody, lpxn antibody, PAAG_03110 antibody, PGTG_11441 antibody

Background: Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, Leupaxin may also function in, and be regulated by, tyrosine kinase activity.

UniProt: O60711