MUC4 antibody (AA 1249-1444)

Catalog No. ABIN3031871

The Rabbit Polyclonal anti-MUC4 antibody is suitable to detect MUC4 in samples from Human and Rat. It has been validated for WB.

Quick Overview for MUC4 antibody (AA 1249-1444) (ABIN3031871)

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MUC4 Antibody

Binding Specificity: AA 1249-1444

Purpose: MUC4 Antibody

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (1249-1444) was used as the immunogen for this MUC4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the MUC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MUC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MUC4

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Alternative Name: MUC4

Background: Mucin 4, also known as MUC4, is a mucin protein that in humans is encoded by the MUC4 gene. Like other mucins, Mucin 4 is a high-molecular weight glycoprotein. It is mapped to 3q29. In normal functioning, Mucin 4 is known to play anti-adhesive roles in the body, such as in lubricating the reproductive lining. It is found in the respiratory tract, particularly in the trachea and lung and the digestive tract, in the esophagus and colon, as well as in the visual and auditory systems. Mucin 4 serves to protect and lubricate the epithelium, which facilitates transport and traps foreign particles. It is found to be overexpressed during the luteal phase of menstruation. Mucin 4 may also have a role in fetal morphogenic development.

Pathways: Regulation of Leukocyte Mediated Immunity